2024.01–现在，广东海洋大学水产学院，教授

2019.12-2021.01 美国马里兰大学，访问学者

2016.12–2023.12，广东海洋大学水产学院，副教授

2013.10–2016.11，广东海洋大学水产学院，讲师

2010.08–2013.09，中科院微生物研究所，助理研究员

中国科学院南海海洋所专业学位硕士兼职指导老师

获得湛江市科技进步一等奖；获得广东海洋大学教学质量优秀奖、授课竞赛二等奖、优秀研究生论文指导奖和本科优秀毕业论文指导奖等荣誉。

长期从事水产动物遗传育种和健康保护相关研究，致力于贝类重要经济性状遗传基础解析、抗病抗逆遗传育种及养殖模式等方面工作，聚焦于企鹅珍珠贝色泽调控育种技术和牡蛎的抗盐抗病遗传育种。

本科生：《水产动物组织胚胎学》、《动物组织学》、《药用海洋生物学》

研究生：《渔业科技与创新》

1、国家自然科学基金，利用大肠杆菌脂肪酸生产长链二元酸（31200081）

2、广东省自然科学基金，企鹅珍珠贝Tyr介导的黑色素合成在先天免疫中的作用及机理研究（2021A1515011052）

3、广东省自然科学基金，ATM-CHK2-P53通路在香港牡蛎高盐适应中的作用及机制研究（2025A1515012727）

4、广东省科技发展专项，企鹅珍珠贝珠层色泽的遗传改良和定向选育技术研究（2016A020210115）

5、广东省渔港建设与渔业发展专项，企鹅珍珠贝珠层色泽的改良和定向选育（B201601-Z08）

6、广东省研究生教育创新计划项目，“水产动物种质资源开发与利用”研究生学术论坛 （2022XSLT_044）

7、广东省高等教育教学改革项目，基于PBL教学法的《组织胚胎学》课程教学改革与实践（粤教高函【2018】180号-296）

8、湛江市科技发展专项，基于黑色素调控的企鹅珍珠贝色泽优化关键技术研究（2022A01047）

1. Feifei Yu, Yishan Lu, Zhiming Zhong, Bingliang Qu, Meifang Wang, Xiangyong Yu*, Jiayu Chen. Mitf involved in innate immunity by activating tyrosinase-mediated melanin synthesis in Pteria penguin. Frontier in immunology. 2021, 12:626493.

2. Zhiming Zhong, Jing Zhang, Baogui Tang,Feifei Yu^*, Yishan Lu, Gang Hou, Jiayu Chen, Zexin Du. Transcriptome and metabolome analyses of the immune response to light stress in the hybrid grouper(Epinephelus lanceolatus ♂ ×Epinephelus fuscoguttatus ♀). Animal. 2022，16 (2): 100448.

3. Yixin Zhang, Qiwen Liang,Feifei Yu* , Jiexiong Zhu , Jianfang Gui, Jinji Lin, Yishan Lu* , Haiyuan Tao.Integration of transcriptome and metabolome reveals tolerance mechanism to high salinity stress inCrassostrea hongkongensis.Aquaculture Reports, 2025,42:102759

4. Wenhao He, Jinji Lin,Feifei Yu*, Yang Leng*, Zhenni Pan, Qiwen Liang, Siying Liu, Xinyue Huang. Identification and function analysis of BCL2 in immune response ofPteria penguin. Fish & Shellfish Immunology, 2024, 149:109574.

5. Feifei Yu, Zexin Du, Zhiming Zhong, Xiangyong Yu, Jiayu Chen, Yishan Lu^*, Jinji Lin.Creb2 involved in innate immunity by activating PpMitf-mediated melanogenesis in Pteria penguin. Fish & Shellfish Immunology, 2023, 138:108809

6. Feifei Yu, Jiayu Chen, Jinji Lin, Zhiming Zhong, Yishan Lu^*, Xiangrong Zeng,Xiaoya Lei. TLR4 involved in immune response against Vibrio Parahaemolyticus by MyD88-dependent pathway in Crassostrea hongkongensis. Fish & Shellfish Immunology, 2023, 134:108591

7. Jiayu Chen, Jinji Lin, Feifei Yu^*, Zhiming Zhong, Qiwen Liang, Huanying Pang, Siyu Wu. Transcriptome analysis reveals the function of TLR4-MyD88 pathway in immune response of Crassostrea hongkongensis againstVibrio Parahemolyticus. Aquaculture Reports, 2022, 25: 101253

8. Feifei Yu,Zhiming Zhong,Jing Zhang,Yong Liu,Jiayu Chen, Baogui Tang*. Light stress affected body color by tyrosinase-mediated melanin synthesis pathway in hybrid grouper.Aquaculture Reports, 2022,23: 101027.

9. Feifei Yu, Xiaoyu Tang; Bingliang Qu*; Zhiming Zhong; Wanyu Zhang; Xiangyong Yu*; Kojic acid inhibited melanin synthesis by tyrosinase pathway in Pteria penguin, Aquaculture Research, 2020, 00:1-8.

10. Feifei Yu, Yibing Zhang∗, Tingkai Liu,Ying Liu, Fan Sun, Jun Jiang, Jianfang Gui∗.Fish virus-induced interferon exerts antiviral function through Stat1 pathway. Molecular Immunology, 2010,47 :2330-2341

11. Feifei Yu, Bingliang Qu*, Dandan Lin, Yuewen Deng, Ronglian Huang and Zhiming Zhong.Pax3 Gene Regulated Melanin Synthesis by Tyrosinase Pathway in Pteria penguin.International Journal of Molecular Science. 2018, 19(12), 3700.

12. Feifei Yu, Zhenni Pan, Bingliang Qu, Xiangyong Yu, Kaihang Xu, Yuewen Deng, Feilong Liang. Identification of a tyrosinase gene and its functional analysis in melanin synthesis ofPteria penguin.Gene, 2018, 656:1-8.

13. Jinji Lin，Ziqi Yu，Yang Leng，Jiexiong Zhu，Feifei Yu*，Yishan Lu*，Jiayu Chen，Wenhao He, Yixin Zhang，Yaoshen Wen.Cloning, Characterization and Functional Analysis of Caspase8-like Gene in Apoptosis of Crassostrea hongkongensis Response to Hyper-Salinity Stress. Fishes, 2024, 9, 172:1-14.

14. Feifei Yu, Xiping Liu, Yong Tao, Kun Zhu. High saturated fatty acids proportion in Escherichia coli enhances the activity of ice-nucleation protein from Pantoea ananatis.FEMS Microbiology letter. 2013, 345(2):141-146

15. Feifei Yu, Meifang Wang, Li Zhou, Jianfang Gui and Xiangyong Yu. Molecular Cloning and Expression Characterization ofDmrt2 inPinctada martensii.Journal of Shellfish Research, 2011, 30(2): 247-254.

授权专利

1． 于非非，曲炳良，鲁义善，余祥勇，钟智明，陈家宇，林金姬. 企鹅珍珠贝Mitf基因的启动子及其应用，发明专利，ZL202210279043.2，授权日2023.7.28

2． 于非非，曲炳良，钟智明，刘永，余祥勇，王梅芳，陈家宇.企鹅珍珠贝Tyr基因的启动子及其应用，发明专利，ZL202110492284.0，授权日2022.11.8

3． 于非非，朱坤，吴金贤，曲炳良，余祥勇，刘永.一种表达高活性冰核蛋白的基因工程菌及其构建方法.发明专利，专利号ZL201910213647.5，授权日2022.9.13 (已转让)

4． 于非非，曲炳良，张丽萍，余祥勇，王梅芳，刘永，潘珍妮.一种育珠前改变企鹅珍珠贝母贝色泽的方法及企鹅珍珠贝母贝色泽检测方法.发明专利，专利号ZL201710937715.3，授权日2021.1.5

5． 于非非，曲炳良，朱坤，余祥勇，王梅芳，刘永，潘珍妮，许开航.一种用于检测生物样品抗冻性的基座及具有其的金属浴.实用新型专利，专利号ZL201720826549.5，授权日2018.1.12