刘泓宇-广东海洋大学水产学院

代表性论文（著作）

[1]Hong-yu Liu,Wu-wei Sun, Bei-ping Tan, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang., 2012. Molecular cloning and expression of hepatopancreas glutamine synthetase in the Pacific white shrimp,Litopenaeus vannamei, induced by acute hypo-osmotic stress.Aquaculture362–363：80–87.

[2]Hong-yu Liu,Jin-fang Yang, Bei-ping Tan, Yingbo Lin, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang., 2014. Effects of dietary potassium on growth, nitrogen metabolism, osmoregulation and immunity in the Pacific white shrimp (Litopenaeus vannamei) reared in low salinity seawater.J Ocean University of China,13 (2): 311-320.

[3]Hongyu Liu,Xinjie Zhang, Beiping Tan*, Yingbo Lin, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang, 2014, Effect of various Na/K ratios in low salinity well water on growth performance and physiological response of Pacific white shrimp,Litopenaeus vannamei.Chinese Journal of Oceanology and Limnology,32(5):991-999.

[4]Hongyu Liu,Zheng Li, Beiping Tan*, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang, 2014, Isolation of a putative probiotic strain S12 and its effect on growth performance, non-specific immunity and disease-resistance of white shrimp,Litopenaeus vannamei.Fish & Shellfish Immunology,41(2):300-307.

[5]Hongyu Liu,Beiping Tan*, Jinfang Yang, Yingbo Lin, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang, 2016, Effects of aqueous Na/K and dietary K on growth and physiological characters of the Pacific white shrimp,Litopenaeus vannamei, reared in low-salt well water.Aquaculture Research,47(2): 540-553.

[6]Hong-yu Liu,Wu-wei Sun, Xiao-hui Dong, Shu-yan Chi, Qi-hui Yang, Yuan-you Li, Bei-ping Tan. 2016. Profiling of Up-Regulated Genes Response to Acute Hypo-Osmotic Stress in Hepatopancreas and Gill of the Pacific White Shrimps (Litopenaeus vannamei).International Journal of Biology. 8(2): 43-57

[7]Liu H.Y.,Dong, X., Chi, S., Yang, Q., Zhang, S., Chen, L., & Tan, B. (2017). Molecular cloning of glucose transporter 1 in grouperEpinephelus coioidesand effects of an acute hyperglycemia stress on its expression and glucose tolerance. Fish physiology and biochemistry, 43(1), 103-114.

[8]Liu H.Y.,Tan, B., Yang, J., Chi, S., Dong, X., & Yang, Q. (2016). Effects of aqueous Na/K and dietary K on growth and physiological characters of the Pacific white shrimp,L itopenaeus vannamei, reared in low‐salt well water. Aquaculture research, 47(2), 540-553.

[9] Li, R.,Liu H.Y（共同第一）.,Dong, X., Chi, S., Yang, Q., Zhang, S., & Tan, B. (2018). Molecular characterization and expression analysis of glucose transporter 1 and hepatic glycolytic enzymes activities from herbivorous fishCtenopharyngodon idellusin respond to a glucose load after the adaptation to dietary carbohydrate levels. Aquaculture, 492, 290-299.

[10] Yin, B.,Liu H.Y.（共同第一）.,Tan, B., Dong, X., Chi, S., Yang, Q., ... & Chen, L. (2018). Cottonseed protein concentrate (CPC) suppresses immune function in different intestinal segments of hybrid grouper♀Epinephelus fuscoguttatus×♂Epinephelus lanceolatuvia TLR-2/MyD88 signaling pathways. Fish & shellfish immunology, 81, 318-328.

[11]Liu, H.Y.,Chen, Q., Tan, B. P., Dong, X. H., Chi, S. Y., Yang, Q. H., ... & Chen, L. Q. (2018). Effects of dietary carbohydrate levels on growth, glucose tolerance, glucose homeostasis and GLUT4 gene expression inTilapia nilotica. Aquaculture Research, 49(12), 3735-3745.

[12] Li, R. X.,Liu, H. Y（*通讯）.,Chen, Q., Tan, B. P., Dong, X. H., Chi, S. Y., ... & Chen, L. Q. (2018). Glucose tolerance of grass carpCtenopharyngodon idellusafter a long‐term adaptation to carbohydrate‐to‐lipid ratio diets. Aquaculture Research, 49(12), 3881-3888.

[13] Li, R. X.,Liu, H. Y（*通讯）.,Li, S. Y., Tan, B. P., Dong, X. H., Chi, S. Y., ... & Chen, L. Q. (2019). Nutritional regulation of gene expression and enzyme activity of phosphoenolpyruvate carboxykinase in the hepatic gluconeogenesis pathway in golden pompano (Trachinotus ovatus). Aquaculture Research, 50(2), 634-643

[14] Li, R., Chen, Q.,Liu H.Y（*通讯）.,Tan, B., Dong, X., Chi, S., ... & Zhang, S. (2019). Molecular characterization and expression analysis of glucose transporter 4 fromTrachinotus ovatus,Rachycentron canadumsandOreochromis niloticusin response to different dietary carbohydrate-to-lipid ratios. Aquaculture, 501, 430-440

[15] Li, R.,Liu H.Y（*通讯）., Li, S., Tan, B., Dong, X., Chi, S., Yang, Q., Zhang, S., (2019). Nutritional regulation of pyruvate kinase and phosphoenolpyruvate carboxykinase at the enzymatic and molecular levels in cobiaRachycentron canadum. Fish Physiology and biochemistry. 45(3):1015-1028

[16] Zhang, W., Liu, K., Tan, B.,Liu, H（*通讯）., Dong, X., Yang, Q., ... & Wang, H. (2019). Transcriptome, enzyme activity and histopathology analysis reveal the effects of dietary carbohydrate on glycometabolism in juvenile largemouth bass, Micropterus salmoides. Aquaculture.504, 39-51.

[17] Chen, Guofeng & Yin, Bin &Liu, Hongyu（*通讯）& Tan, Beiping & Dong, Xiaohui & Yang, Qihui & Chi, Shuyan & Zhang, Shuang. (2020). Effects of fishmeal replacement with cottonseed protein concentrate on growth, digestive proteinase, intestinal morphology and microflora in pearl gentian grouper (♀Epinephelus fuscoguttatus×♂Epinephelus lanceolatu). Aquaculture Research. 51(7):2870-2884.

[18] Ayiku, Stephen & Jianfei, Shen & Tan, Bei-ping & Dong, Xiao-Hui &Liu, Hong-yu（*通讯）. (2020). Effects of dietary yeast culture on shrimp growth, immune response, intestinal health and disease resistance against Vibrio harveyi. Fish & Shellfish Immunology. 102：286-295.

[19] Shen, J.,Liu, H（*通讯）., Tan, B., Dong, X., Yang, Q., Chi, S., & Zhang, S. (2020). Effects of replacement of fishmeal with cottonseed protein concentrate on the growth, intestinal microflora, haematological and antioxidant indices of juvenile golden pompano (Trachinotus ovatus). Aquaculture Nutrition,26(4):1119-1130.

[20] Stephen Ayiku, Jianfei Shen, Bei-ping Tan, Xiao-hui Dong,Hong-yu Liu（*通讯）.(2020). Effects of reducing dietary fishmeal with yeast supplementations on Litopenaeus vannamei growth, immune response and disease resistance against Vibrio harveyi.Microbiological Research,239:126554

[21] BinYin，HongyuLiu（共同第一），BeipingTan，XiaohuiDong，ShuyanChi，QihuiYang，ShuangZhang.(2020). Preliminary study of mechanisms of intestinal inflammation induced by plant proteins in juvenile hybrid groupers (♀Epinephelus fuscoguttatus×♂E. lanceolatu).Fish & Shellfish Immunology.106：341-356

[22] Yin B,Liu H（共同第一）, Tan B, Dong X, Chi S, Yang Q, Zhang S. MHC II-PI3K/Akt/mTOR Signaling Pathway Regulates Intestinal Immune Response Induced by Soy Glycinin in Hybrid Grouper: Protective Effects of Sodium Butyrate. Frontiers in Immunology. 2021 Jan 18;11:615980. doi: 10.3389/fimmu.2020.615980. PMID: 33537033; PMCID: PMC7849651.

[23] Guofeng Chen, Jiahao Qian,Hongyu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Qihui Yang, Shuyan Chi, Shuang Zhang.(2021).Dietary carbohydrate-to-lipid ratios modulate juvenile hybrid grouper (♀Epinephelus fuscoguttatus× ♂E. lanceolatus): Effects on growth, serum biochemistry, intestinal digestion and hepatic metabolism of glucose and lipid.Aquaculture Nutrition.27（5）：1370-1382

[24] Yin B,Liu H（共同第一）, Tan B, Dong X,Chi S, Yang Q and Zhang S (2021)Dynamic Alterations of the Distal Intestinal Microbiota,Transcriptome,and Metabolome of Hybrid Grouper by b-Conglycinin With Reconciliations by Sodium Butyrate in Feed. Front. Mar. Sci. 8:705332. doi: 10.3389/fmars.2021.705332

[25] Chen G, Yin B,Liu H（*通讯）, Tan B, Dong X,Yang Q, Chi S and Zhang S (2021)Supplementing Chitosan Oligosaccharide Positively Affects Hybrid Grouper (Epinephelus fuscoguttatus♀ ×E. lanceolatus♂) Fed Dietary Fish Meal Replacement With Cottonseed Protein Concentrate: Effects on Growth, Gut Microbiota, Antioxidant Function and Immune Response. Front. Mar. Sci. 8:707627. doi: 10.3389/fmars.2021.707627

[26] Yin, B.,Liu, H（共同第一）., Tan, B. et al. Dietary supplementation of β-conglycinin, with or without sodium butyrate on the growth, immune response and intestinal health of hybrid grouper. Sci Rep 11, 17298 (2021).https://doi.org/10.1038/s41598-021-96693-x

[27] Jiahao Qian, Bin Yin,Hongyu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Shuyan Chi, Qihui Yang, Shuang Zhang,Effects of taurine supplementation in a high-carbohydrate diet on growth performance, plasma biochemical, digestive and glucose metabolism enzymes in hybrid grouper (♀Epinephelus fuscoguttatus× ♂E. lanceolatus),Aquaculture Reports,2021(21): 100820

[28] Yin, B.,Liu, H（*通讯）., Tan, B., Dong, X., Chi, S., Yang, Q., & Zhang, S. (2021). Supplementing tributyrin to cottonseed protein concentrate-based diets can improve growth performance, lipid metabolism and distal intestinal immunity in hybrid grouper (Epinephelus fuscoguttatus♀ ×Epinephelus lanceolatus♂). Aquaculture Nutrition, 00, 1–14.https://doi.org/10.1111/anu.13370

[29] Qi Wang, Stephen Ayiku,Hongyu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Shuyan Chi, Qihui Yang, Shuang Zhang, Wenhao Zhou,Effects of dietary ESTAQUA? yeast culture supplementation on growth, immunity, intestinal microbiota and disease-resistance against Vibrio harveyi in hybrid grouper (♀Epinephelus fuscoguttatus×♂E. lanceolatus),Aquaculture Reports,22,2022,100922,

[30] Ling Pan, Jianfei Shen,Hongyu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Qihui Yang, Shuyan Chi, Shuang Zhang,Molecular cloning and characterization of GLUT2 from pompano (Trachinotus ovatus), and its gene expression in response to exogenous enzymes supplementation in high carbohydrate diet,Aquaculture Reports,V22,2022,100999

[31] Chen, G., Qian, J.,Hong-yu Liu（*通讯）., Tan, B., Dong, X., Yang, Q., Chi, S., & Zhang, S. (2022). Metabolic responses of hybrid grouper (♀Epinephelus fuscoguttatus×♂E. lanceolatus) induced by different feeding modes: Effects on growth, serum biochemical indices, intestinal digestion and hepatic metabolism of glucose and lipid. Aquaculture Research, 2022, 53(7): 2708-2723

[32] Li W K, Pan L,Hong-yu Liu（*通讯）,Effects of the Clostridium butyricum on growth performance, antioxidant capacity, immunity and disease resistance of Litopenaeus Vannamei fed with cottonseed protein concentrate (CPC) replacement of fishmeal in diet [J]. Fish & shellfish immunology, 2022, 126: 283-291

[33]Hongyu Liu, Guofeng Chen, Lixian Li, Zhixuan Lin, Beiping Tan, Xiaohui Dong, Qihui Yang, Shuyan Chi, Shuang Zhang, Xiaoqiu Zhou,Supplementing artemisinin positively influences growth, antioxidant capacity, immune response, gut health and disease resistance againstVibrio parahaemolyticusinLitopenaeus vannameifed cottonseed protein concentrate meal diets,Fish & Shellfish Immunology,2022,131,105-118

[34] Chao Li, Guofeng Chen, Menglin Wei,Hong-yu Liu（*通讯）,Beiping Tan, Xiaohui Dong, Qihui Yang, Shuyan Chi, Shuang Zhang, Min Yao,Dietary sulfate-based alginate polysaccharide supplementation boosts growth, gut health, immune response and disease resistance injuvenile hybrid grouper (♀Epinephelus fuscoguttatus× ♂E. lanceolatus) fed cottonseed protein concentrate-based diets,Aquaculture Reports,28,2023,101441

[35]Liu, H.; Pan, L.; Shen, J.;Tan, B.; Dong, X.; Yang, Q.; Chi, S.;Zhang, S. Effects of Carbohydrase Supplementation on Growth Performance, Intestinal Digestive Enzymes and Flora, Glucose Metabolism Enzymes, and glut2 Gene Expression of Hybrid Grouper (Epinephelus fuscoguttatus E.lanceolatus) Fed Different CHO/L Ratio Diets. Metabolites 2023, 13, 98. https://doi.org/10.3390/ metabo13010098

[36] Lixian Li,Hong-yu Liu（*通讯）, Weikang Li, Qi Wang, Zhixuan Lin, Beiping Tan, Xiaohui Dong, Ruitao Xie, Clostridium butyricum improves the digestive enzyme activity, antioxidant and immunity related genes expression and intestinal microbiota of Litopenaeus vannamei fed a replacing fishmeal with cottonseed protein concentrate (CPC) diet, Aquaculture Reports,29,2023,101517

[37] Zhixuan Lin, Ling Pan, Ruitao Xie, Lixian Li, Jiasheng Wen, Xiaoqiu Zhou, Xiaohui Dong, Shiwei Xie, Beiping Tan,Hong-yu Liu（*通讯）, Effects of dietary artemisinin on growth performance, digestive enzyme activity, intestinal microbiota, antioxidant capacity and immune biomarkers of Coral trout (Plectropomus leopardus), Aquaculture Reports, 29, 2023, 101525

[38] Qi Wang, Weikang Li,Hong-yu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Shuyan Chi, Qihui Yang, Shuang Zhang, Depeng Fan, Yadong Hu, The isolation, identification, whole-genome sequencing of Clostridium butyricum LV1 and its effects on growth performance, immune response, and disease-resistance ofLitopenaeus vannamei, Microbiological Research,272, 2023, 127384

[39]Ling Pan, Weikang Li, Ruitao Xie,Hong-yu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Qihui Yang, Shuyan Chi and Shuang Zhang. Effects of Clostridium butyricum on Growth Performance,Intestinal Health, and Disease Resistance of Hybrid Grouper (Epinephelus fuscoguttatus♀ ×E. lanceolatus♂) Fed with Cottonseed Protein Concentrate (CPC) Replacement of Fishmeal.Aquaculture Nutrition, 2023, 1184252

[40] Pan L, Qian J,Hong-yu Liu（*通讯）, Tan B, Dong X, Yang Q, Chi S, Zhang S. Implications on growth performance, glucose metabolism, PI3K/AKT pathway, intestinal flora induced by dietary taurine in a high-carbohydrate diet for grass carp (Ctenopharyngodon idella). Br J Nutr. 2023 Jul 26:1-14. doi: 10.1017/S0007114523001502. Epub ahead of print. PMID: 37492950.

[41] Yin, Bin & Liu,Hong-yu Liu（*通讯）& Tan, Beiping & Deng, Junming & Xie, Shiwei. (2023). The effects of sodium butyrate (NaB) combination with soy saponin dietary supplementation on the growth parameters, intestinal performance and immune-related genes expression of hybrid grouper (Epinephelus fuscoguttatus♀ ×E. lanceolatus♂). Fish & Shellfish Immunology. 141. 109033. 10.1016/j.fsi.2023.109033.

[42]Liu, H.; Wei, M.; Tan, B.; Dong, X.; Xie, S. The Supplementation of Berberine in High-Carbohydrate Diets Improves Glucose Metabolism of Tilapia (Oreochromis niloticus) via Transcriptome, Bile Acid Synthesis Gene Expression and Intestinal Flora. Animals 2024, 14, 1239.https://doi.org/10.3390/ani14081239

[43] Qi Wang, Depeng Fan, Yadong Hu,Hong-yu Liu（*通讯）, Beiping Tan, Shiwei Xie, Supplementation of Clostridium butyricum LV1 lyophilised powder to cottonseed protein concentrate basal diets improves growth, intestinal microbiota, and immunity of Litopenaeusvannamei, Aquaculture,593,2024,741334,

[44] Lixian Li, Ling Pan, Zhixuan Lin, Jiasheng Wen, Beiping Tan,Hong-yu Liu（*通讯）, Yi Hu,Metformin improves insulin resistance, liver healthy and abnormal hepatic glucolipid metabolism via IR/PI3K/AKT pathway in Ctenopharyngodon idella fed a high-carbohydrate diet,Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology,283,2024,109976,

[45] Baoqiang Liu,Hong-yu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Shiwei Xie, Weiyu Deng,Effects of enzymatic soybean phospholipid replacing soybean oil on growth performance, glycolipid metabolism and intestinal flora of largemouth bass (Micropterus salmoides),Aquaculture Reports,38,2024,102280,

[46] Zhixuan Lin, Ling Pan, Ruitao Xie, Lixian Li, Jiasheng Wen, Xiaoqiu Zhou, Xiaohui Dong, Shiwei Xie, Beiping Tan,Hong-yu Liu（*通讯）,Artemisinin supplementation improves growth, lipid metabolism, and intestinal microbiota of golden pompano (Trachinotus ovatus) fed high cottonseed meal diets,Aquaculture Reports,39,2024,102479

[47] Wang, Q., Fan, D.,Hong-yu Liu（*通讯）. et al. Effects of supplementation with freeze-dried Clostridium butyricum powder after replacement of fishmeal with cottonseed protein concentrate on growth performance, immune response, and intestinal microbiota of Litopenaeus vannamei. BMC Vet Res 20, 519 (2024). https://doi.org/10.1186/s12917-024-04372-6

[48] Jiasheng Wen, Qintong Yu, Ling Pan,Hong-yu Liu（*通讯）, Beiping Tan, Xiaohui Dong, Shuyan Chi, Qihui Yang, Shuang Zhang,Effects of metformin supplementation in high-carbohydrate diets on growth performance, glucose metabolism, intestinal flora, and PI3K/AKT signaling pathway of hybrid grouper (Epinephelus fuscoguttatus♀×Epinephelus lanceolatu♂),Aquaculture Reports,39,2024,102508,

[49] Qi Wang, Depeng Fan, Yadong Hu,Hong-yu Liu（*通讯）, Beiping Tan, Shiwei Xie, Qiang Chen,Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei,Aquaculture Reports,39,2024,102533

[50]刘泓宇,张新节,谭北平,董晓慧, 迟淑艳、杨奇慧.饲料钾水平对低盐井水养殖凡纳滨对虾生长及生理特性的影响,中国水产科学,2014. 21(2): 321-329.

[51]刘泓宇,谭北平,董晓慧, 迟淑艳、杨奇慧.低盐胁迫下凡纳滨对虾鳃丝抑制性消减杂交cDNA文库构建及差异EST分析.海洋湖沼通报,2014. (1): 56-66.

[52]刘泓宇,毛义波,谭北平,等.饲料糖水平对不同食性鱼类生长及葡萄糖耐受能力的影响[J].水产学报,2015, 39(12): 1852-1862.

[53] 申建飞,陈铭灿,刘泓宇(通讯),谭北平,董晓慧,杨奇慧, ... &王华朗. (2019).浓缩棉籽蛋白替代鱼粉对卵形鲳鲹幼鱼生长性能,血清生化指标,肝脏抗氧化指标及胃肠道蛋白酶活性的影响.动物营养学报, 31(2), 746-756.

师资队伍

杰出人才

专任教师

博士后

专业技术人员

外聘教师

荣休教师

水产养殖系

刘泓宇

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代表性论文（著作）