2025.07至今 广东海洋大学水产学院 教授

2018.01-2025.06广东海洋大学水产学院，副教授

2014.07-2017.12广东海洋大学水产学院，讲师

Animals，Fishes客座编辑；

湛江市水产学会副秘书长；

湛江市海洋生态与养殖环境重点实验室主任。

2015年湛江市科技进步二等奖

2019年广东海洋大学十佳班主任

2024年广东海洋大学教学名师

2024年广东省学位与研究生教育学会教学成果一等奖

养殖环境调控，生态毒理，养殖尾水处理，智慧渔业

本科生：《普通生态学》《动物生物化学》《海洋生态学》

研究生：《分子生态学》《水域生态学》

1.广东省自然科学基金：海水酸化背景下凡纳滨对虾对Cu胁迫的响应机理（2025A1515010949）；

2. 广东省普通高校重点领域专项（科技服务乡村振兴）：基于海上风电平台的卵形鲳鲹深海网箱高效养殖技术研究(2023ZDZX4013)。

3. 广东省农业农村厅：第四轮广东省现代农业产业（虾蟹）技术体系创新团队（岗位专家）。

4. 国家自然科学基金：铜离子胁迫下凡纳滨对虾免疫相关MicroRNA的筛选鉴定与功能研究（31600321）.

5.广东省自然科学基金：铜离子胁迫下凡纳滨对虾血细胞的响应机理研究（2015A030310438）

[1]Zou YF, Cao PH, Bao ZM, Xu Yu, Xu ZQ, Guo H*. Histological, physiological and transcriptomic analysis in hepatopancreas ofProcambarus clarkiiunder heat stress, Ecotoxicology and Environmental Safety, 2025, 289: 117459.

[2]Su XB, Cao PH, Zhang S, Liang Z, Zhang JY, Guo JY, Zhu XW, Guo H*. Integrated proteomics and metabolomics analysis reveals the impact of zinc exposure on hepatopancreas fromLitopenaeus vannamei: Insights into the response mechanisms, Aquaculture Reports, 2025, 43: 102879.

[3]Liu JH, Li JT, Lu YP, Zheng PH, Zhang ZL, Zhang XX, Xu C, Yu ZH, Yang XY, Guo H*, Xian JA*. Complementary DNA (cDNA) cloning and expression analysis of selenium glutathione peroxidase (Se-GPx) and glutathione S-transferases (GST) 1 in red claw crayfish (Cherax quadricarinatus), Comparative Biochemistry and Physiology, Part A, 2025,306: 111876.

[4]Xu C, Lu YP, Zhang ZL, Hao CG, Yu ZH, Li JT, Zheng PH, Zhang XX, Yang XY, Guo H*, Xian JA*. Effects of dietary sharp-leaf galangal (Alpinia oxyphylla) fruit extract on growth, muscle composition, immune responses, gut flora, and disease resistance in juvenile red claw crayfish (Cherax quadricarinatus), Aquaculture Reports, 2025, 43: 102870.

[5] Su XB, Zhu XW, Liang Z, Bao ZM, Zhang JY, Guo JY, Guo H*. Biochemical, histological and transcriptional response of intestines inLitopenaeus vannameiunder chronic zinc exposure, Chemosphere, 2024, 354: 141646.

[6] Su XB, Li T, Zhu XW, Zheng PH, Pan HK, Guo H*. Exploring the impact of nonylphenol exposure onLitopenaeus vannameiat the histological and molecular levels, Ecotoxicology and Environmental Safety, 2024,279:116475.

[7] Zheng PH, Lu YP, Zhang XX, Luan KE, Zhang ZL, Li JJ, Xu T, Li JT, Xian JA*, Guo H*, Wang AL*. New insights into the regulation mechanism of Pacific white shrimp (Litopenaeus vannamei) hepatopancreas under 4-nonylphenol exposure using transcriptome analysis, Fish & Shellfish Immunology, 2023,141:109050.

[8] Liang Z, Chen TC, Yang FR, Li SH, Zhang S, Guo H*. Toxicity of chronic waterborne zinc exposure in the hepatopancreas of white shrimpLitopenaeus vannamei, Chemosphere, 2022,309:136553.

[9 ]Liang Z, Liang JR, Li L, Chen TC, Guo H*. NADPH oxidase involved in immune response via regulating the expression of antioxidant genes inLitopenaeus vannamei, Aquaculture Reports, 2021,21:100810.

[10]Guo H, Liang Z, Zheng PH, Li L, Xian JA, Zhu XW*. Effects of nonylphenol exposure on histological changes, apoptosis and time-course transcriptome in gills of white shrimpLitopenaeus vannamei, Science of the Total Environment,2021,781: 0-146731.